From Ask Dr Wiki
Characteristics
- Autonomic failure associated with somatic nerve deficits
- Presents as syncope and near syncope
- First described by Shy and Drager
Symptoms
- Consist of Orthostatic Hypotension, urinary and rectal incontinence, loss of sweating, iris atrophy, external ocular palsies, rigidity, tremor, loss of associated movements, impotence, atonic bladder, loss of rectal sphincter tone, fasciculations, wasting of distal muscles, EMG that suggest involvement of the anterior horn cells, and findings of a neuropathic lesion in the muscle biopsy.
- Onset is usually in the 5th to 7th decade
Subgroups
- Parkinsonian
- Cerebellar
- Mixed
