Usual interstitial pneumonia

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Usual interstitial pneumonia, commonly abbreviated UIP, is the name of a histopathological pattern seen in diffuse lung diseases. Diffuse lung diseases are also referred to as interstitial lung diseases.

UIP is a type of idiopathic interstitial pneumonia. Sometimes, confusingly, it is used as a synoym for idiopathic pulmonary fibrosis.

Contents

Differential diagnosis

UIP is seen in:[1]

Histologic appearance

UIP is characterized by:

  • interstitial inflammation,
  • fibroblast foci,
  • (microscopic) honeycombing and
  • patchy lesional distribution (heterogeneous areas of abnormal and normal lung).

History and application of term

UIP, as a term, first appeared in the pathology literature. It was coined by Averill Abraham Liebow.[3]

It is sometimes, confusingly, used to refer to idiopathic pulmonary fibrosis, one of its many clinical correlates.

Pneumonia misnomer?

The definition of "pneumonia" is often described as a '... lung inflammation caused by a virus, bacteria or irritant.'[4]

Etymologically, the usage of "pneumonia" in UIP is correct; the word "pneumonia" is derived from "pneumon" (lung) and the suffix "-ia" (condition).[5]

See also

References

  1. ↑ Leslie KO, Wick MR. Practical Pulmonary Pathology: A Diagnostic Approach. Elsevier Inc. 2005. ISBN 978-0-443-06631-3.
  2. ↑ {{#if:Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC |{{#if: |[[{{{authorlink}}}|{{#if: |{{{last}}}{{#if: |, {{{first}}} }} |Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC }}]] |{{#if: |{{{last}}}{{#if: |, {{{first}}} }} |Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC }} }} }}{{#if:Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC |{{#if: | ; {{{coauthors}}} }} }}{{#if: | ({{{date}}}) |{{#if:2000 |{{#if: | ({{{month}}} 2000) | (2000) }} }} }}{{#if:Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC | . }}{{#if:Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC2000 | }}{{#ifeq: | no | | {{#if: |“|"}} }}{{#if: |[{{{url}}} Pulmonary drug toxicity: radiologic and pathologic manifestations] |Pulmonary drug toxicity: radiologic and pathologic manifestations }}{{#ifeq: | no | | {{#if:|”|"}} }}{{#if: | (in {{{language}}}) }}{{#if: | ({{{format}}}) }}{{#if:Radiographics : a review publication of the Radiological Society of North America, Inc |. Radiographics : a review publication of the Radiological Society of North America, Inc }}{{#if:20 | 20 }}{{#if:5 | (5) }}{{#if:1245–59 |: 1245–59 }}{{#if: |. {{#if: |{{{location}}}: }}{{{publisher}}} }}{{#if: |. doi:[1] }}{{#if: |. ISSN {{{issn}}} }}{{#if:10992015 |. PMID 10992015 }}{{#if: |. Bibcode: {{{bibcode}}} }}{{#if: |. OCLC {{{oclc}}} }}{{#if: |. {{{id}}} }}{{#if: |. Retrieved on [[{{{accessdate}}}]]{{#if: | , [[{{{accessyear}}}]] }} }}{{#if: | Retrieved on {{{accessmonthday}}}, {{{accessyear}}} }}{{#if: | Retrieved on {{{accessdaymonth}}} {{{accessyear}}} }}{{#if: |. [{{{laysummary}}} Lay summary]{{#if: | – {{{laysource}}}}} }}{{#if: | ([[{{{laydate}}}]]) }}.{{#if: | “{{{quote}}}” }}
  3. ↑ Averill Abraham Liebow. whonamedit.com. URL: http://www.whonamedit.com/doctor.cfm/2548.html. Accessed on: November 12, 2007.
  4. ↑ Pneumonia. dictionary.com. URL: http://dictionary.reference.com/browse/pneumonia. Accessed on: November 14, 2007.
  5. ↑ Pneumonia. Stedman's Medical Dictionary. URL: http://www.emedicine.com/asp/dictionary.asp?keyword=pneumonia. Accessed on: November 12, 2007.
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