Restrictive Cardiomyopathies

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Definition

  • A group of disorders that affect myocardial function by either primary myocyte dysfunction and/or extracellular infiltration and fibrosis
  • Predominant feature is impaired ventricular filling/diastolic dysfunction with preservation of systolic function (early in disease).
  • Most are rapidly progressive and irreversible with transplantation being the only treatment option for advanced disease.

Etiology of RCM

Primary

  • Loeffler’s
  • Idiopathic
  • Endomyocardial Fibrosis

Secondary

  • Infiltrative
  • Sarcoidosis
  • Amyloidosis
  • Post-Radiation
  • Storage Disease
  • Fabry’s
  • Hemochromatosis
  • Glycogen Storage
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