Carotid Sinus Syndrome

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Background

  • Carotid Sinus Syndrome is diagnosed with Carotid Sinus Massage.
  • This procedure should be avoided in patients with carotid bruits or a history of cerebrovascular events or transient ischemic attacks
  • This reflex response has two components:
    • A cardioinhibitory component, due to enhanced parasympathetic tone, manifested by slowing of the sinus rate or prolongation of the PR interval and advanced atrioventricular block, alone or in combination with
    • A vasodepressor component, due to decreased sympathetic activity, resulting in loss of vascular tone and hypotension, independent of changes in heart rate.
  • Carotid sinus hypersensitivity is diagnosed when a ≥ 50 mm Hg reduction in systolic blood pressure or a ventricular pause of ≥ 3 s occurs when a 5-10 s carotid sinus massage is done.
  • The prevalence increases with age and with comorbidities (cardiovascular, cerebrovascular,and neurodegenerative) and may be present in up to 45% of elderly patients with syncope, falls, and dizziness.

References

  1. Neurocardiogenic syncope. Carol Chen-Scarabelli, Tiziano M Scarabelli. BMJ 2004;329:336–41
  2. Brignole M, Alboni P, Benditt D, Bergfeldt L, Blanc JJ, Bloch Thomsen PE, et al for the Task Force on Syncope, European Society of Cardiology. Guidelines on management (diagnosis and treatment) of syncope. Eur Heart J 2001;22:1256-306.
  3. Gregoratos G, Cheitlin M, Conill A, Epstein AE, Fellows C, Ferguson TB Jr, et al. ACC/AHA guidelines for implantation of cardiac pacemakers and antiarrhythmia devices: executive summary—a report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee on pacemaker implantation). Circulation 1998;97:1325-35.
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